El cáncer es considerado un conjunto de enfermedades que se caracterizan por el crecimiento celular desregulado, invasión y propagación de células desdiferenciadas desde un sitio de origen a otros sitios del cuerpo, lo que se conoce también como metástasis. El hepatocarcinoma (HCC) es un tipo de cáncer que se genera...
Methods. Two HIV-1 lymphotropic reference strains with X4 tropism: HIV-1IIIB and HIV-1MN, MT2 human lymphocyte cell line and CS from shark cartilage as a positive inhibition control of HIV infection in vitro were used. Inhibition assays were performed by preincubation of serial dilutions of human milk GAGs and CS (for...
Cancer cells are characterized by alterations in key metabolic pathways to fulfill the biosynthetic demands associated with proliferation. Part of this phenotype is translated in a significant reliance in the use of glucose as an energy source, and a greater synthesis of lipids to favor cell proliferation. The growth differentiation...
El cáncer de mama es una enfermedad de interés global por su alta tasa de incidencia y mortalidad. Actualmente es ampliamente utilizada la presencia de marcadores inmunohistoquimicos. En este trabajo nos centramos en el subtipo Luminal A (ER+/PR+/HER2-) ya que es el de mejor pronóstico y responde a tratamiento, y...
El virus de influenza H1N1 (2009), es considerado una emergencia sanitaria a nivel mundial; se ha descrito que durante el 2009 ocasionó 151,700 a 575,400 muertes en todo el mundo afectando mayoritariamente a personas menores de 65 años. El virus de Influenza comúnmente infecta el tracto superior respiratorio resultando en...
Background: Chemotherapy is the backbone of systemic treatment for triple negative breast cancer (TNBC), which is one of the most relevant breast cancers molecular types due to the ability of tumor cells to develop drug resistance, highlighting the urgent need to develop newer and safer drug combinations for treatment. In...
During the stage of endogenous deficiency, the metabolism of women and the mechanisms that regulate oxidative stress are not the exception. Oxidative stress is associated with a part with the increase of free radicals and with modifications both in the activity of antioxidant enzymes and on the other side of...
Auxin and insulin promote maize (Zea mays) embryo growth, induce S6 ribosomal protein (S6rp) phosphorylation, and promote specific protein synthesis. The objective of this research was to test a possible cross-talk between insulin and auxin transduction pathway in maize coleoptiles, typical auxin target tissue. Auxin and insulin produced differential quantitative...
