Background: Chemotherapy is the backbone of systemic treatment for triple negative breast cancer (TNBC), which is one of the most relevant breast cancers molecular types due to the ability of tumor cells to develop drug resistance, highlighting the urgent need to develop newer and safer drug combinations for treatment. In...
During the stage of endogenous deficiency, the metabolism of women and the mechanisms that regulate oxidative stress are not the exception. Oxidative stress is associated with a part with the increase of free radicals and with modifications both in the activity of antioxidant enzymes and on the other side of...
Auxin and insulin promote maize (Zea mays) embryo growth, induce S6 ribosomal protein (S6rp) phosphorylation, and promote specific protein synthesis. The objective of this research was to test a possible cross-talk between insulin and auxin transduction pathway in maize coleoptiles, typical auxin target tissue. Auxin and insulin produced differential quantitative...
Synaptic vesicle protein 2A (SV2A) has become an attractive target of investigation due to its possible role in the pathophysiology of epilepsy. This protein is expressed ubiquitously in all nerve terminals independently of their neurotransmitter content. A decrease in SV2A levels has been reported in patients with refractory epilepsy and...
Durante la germinación de las semillas, se reactiva el metabolismo, se repara el ADN y se reinicia la división celular en los meristemos. Sin embargo, los mecanismos que coordinan el crecimiento y la división celular en los ejes embrionarios de maíz en germinación no se comprenden completamente. Se ha reportado...
