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  1. Papel de los genes srrA y msnA en la biosíntesis de lovastatina por Aspergillus terreus

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    Descrição: Lovastatin is a drug of great industrial importance for reducing blood cholesterol levels, also in recent years is found as potential cancer therapeutic functions. Its conventional production takes place in SmF, however, in recent years has aroused great interest in the production SSF by high production, among other advantages over...
    Sujeito: Cholesterol, Metabolitos, Metabolism, Colesterol, Metabolismo, and Metabolites
    O Criador: Bibián León, María Esmeralda
    Contribuinte: Miranda Labra, Roxana Uri, Gómez Quiroz, Luis Enrique, Mejía Álvarez, Armando, Barrios González, Javier, and Tarragó Castellanos, María del Rosario
    Editor: Universidad Autónoma Metropolitana
    Posgrado: Maestria en Biotecnologia
    Língua: spa
    Año de publicación: 2015
    Direitos: Acceso Abierto
    Licença: Atribucion-NoComercial 4.0 Internacional (CC BY-NC 4.0)
    Tipo de Recurso: Tesis de Maestría
    Identificador: https://doi.org/10.24275/uami.rj430480f

  2. Papel de las Especies Reactivas de Oxígeno en la biosíntesis de Penicilina G, Cefalosporina C y Lovastatina

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    Descrição: In previous work on the production of lovastatin by Aspergillus terreus, we found that the concentration of reactive oxygen species (ROS) increased to high levels precisely at the beginning of the production phase (idiophase) and that these levels were maintained throughout the idiophase. Furthermore, ROS were shown to regulate lovastatin...
    Sujeito: Estrés oxidativo, Biosíntesis, Oxidative stress, Penicilina, Biotechnology, Biotecnología, Penicillin, Cefalosporina, Especies reactivas del oxígeno, Statins (Cardiovascular agents), Cephalosporins, Lovastatina, and Biosynthesis
    O Criador: Bibián León, María Esmeralda
    Contribuinte: Miranda Labra, Roxana Uri, Mejía Álvarez, Armando, Barrios González, Javier, Pérez Sánchez, Ailed, and Gómez Quiroz, Luis Enrique
    Editor: Universidad Autónoma Metropolitana
    Posgrado: Doctorado en Biotecnologia
    Língua: spa
    Año de publicación: 2021
    Direitos: Acceso Abierto
    Licença: Atribucion-NoComercial 4.0 Internacional (CC BY-NC 4.0)
    Tipo de Recurso: Tesis de Doctorado
    Identificador: https://doi.org/10.24275/uami.pg15bf11c