Obesity-osteosarcopenic (OSO) occurs when there is a loss of bone density (osteoporosis), muscle mass and strength (sarcopenia), this combination with an increase in the proportion of adipose tissue (obesity). OSO causes a number of comorbidities; being the decrease in physical activity, loss of mobility, among others. Its origin is multifactorial,...
Cellular senescence and gliosis in the brain play a crucial role in the development of neurodegenerative diseases and cognitive decline. Factors such as oxidative stress induced by a high-fat diet have been identified as promoters of these phenotypes in the brain. This study aims to identify changes in epigenetic marks...